Circulating Endothelial-Derived Activated Microparticle: A Useful Biomarker for Predicting One-Year Mortality in Patients with Advanced Non-Small Cell Lung Cancer

Table 3

Predictors of 1-year mortality in non-small cell lung cancer patients by univariate analysis and multivariate logistic regression analysis.

Variable	Comparison	Univariate; OR^b (95% CI^c)	𝑃 value	Multivariate; OR^b (95% CI^c)	𝑃 Value
Gender	Male versus female	3.744 (1.671~8.391)	0.001	4.676 (1.542~14.175)	0.006
Liver metastasis	Yes versus no	6.000 (1.231~29.233)	0.027
Brain metastasis	Yes versus no	2.667 (0.920~7.730)	0.071	5.378 (1.012~28.582)	0.048
First-line treatment status	Disease control versus progression	0.363 (0.162~0.811)	0.013
Performance status	2 versus 0 & 1	9.935 (1.163~84.878)	0.036
Charlson comorbidity index	Per 1 unit decrease	0.813 (0.674~0.981)	0.031
CD31^+CD42b^−AN-V^− (counts/mL)^a	Per 1 unit decrease	0.9996 (0.999~1.000)	0.021	0.9995 (0.999~1.000)	0.007

aCD31⁺CD42b⁻AN-V⁻ = endothelial-derived activated microparticle.
^bOdds ratio.
^cConfidence interval.