Cartilage Dysfunction in ALS Patients as Side Effect of Motion Loss: 3D Mechano-Electrochemical Computational Model
Figure 1
Schematic illustration of articular cartilage microstructure and its main components. (a) Constituents of the cartilage tissue: chondrocytes, proteoglycans complex, collagen fibers, and ions dissolved in the interstitial fluid. (b) Proteoglycan macromolecule aggregate with charged-glycosaminoglycan side chains attached to a hyaluronic chain.
