Research Article
Cartilage Dysfunction in ALS Patients as Side Effect of Motion Loss: 3D Mechano-Electrochemical Computational Model
Table 2
3D free swelling model for healthy cartilage parameters.
| Description | Symbol | Value | Refs |
| Initial thickness of the sample | | 0.5 mm | [26] | Initial diameter of the sample | | 1.5 mm | [26] | Number of mesh elements | NELEM | 760 | [26] | Number of mesh nodes | NNODES | 1026 | — | Young’s modulus | | Pa | [15] | Poisson coefficient | | 0.28 | [15] | Drag coefficient between the solid and the water phase | | N·s·m−4 | [26] | Diffusivity of the cations | | m·s−1 | [26] | Diffusivity of the anions | | m·s−1 | [26] | Initial FCD | | 0.2 mEq·mL−1 | [26] | Activity coefficient of cations | | 0.86 | [6] | Activity coefficient of anions | | 0.85 | [6] | Gas constant | | 8.314 J·mol−1·K−1 | [26] | Absolute temperature | | 298 K | [26] | Osmotic coefficient | | 0.8 | [6] | Initial amount of water in the tissue | | 0.75 | [26] |
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