Evaluation of the Influence of Formulation and Process Variables on Mechanical Properties of Oral Mucoadhesive Films Using Multivariate Data Analysis

Table 4

Models for films with nonwoven textile.

		Pen. strength	Pen. work	Pen. def.	Ten. strength	Ten. work	Ten. def.
Significance (𝑃 value)	Model	0.000	0.003	0.006	0.000	0.000	0.049
	mL of glycerol	0.000	0.004	0.002	0.000	0.000	0.803
	Thickness	0.000	0.018	0.284	0.000	0.002	0.029
	mL of glycerol * thickness	0.000	0.012	0.033	0.000	0.007	0.052
Goodness of fit	𝑅-square	0.98	0.81	0.77	1.00	0.90	0.61
	𝑅-square prediction	0.96	0.58	0.49	0.99	0.77	0.11
	C.V. in %	9.83	17.64	9.97	4.67	14.46	8.15