Bortezomib Treatment Produces Nocifensive Behavior and Changes in the Expression of TRPV1, CGRP, and Substance P in the Rat DRG, Spinal Cord, and Sciatic Nerve

Figure 9

Double labeling immunofluorescence for TRPV1/CGRP ((a–c) and (d–f)) and TRPV1/SP ((g–i) and (j–l)) in lumbar spinal cord dorsal horn from control (ctrl) ((a–c) and (g–i)) and chronically BTZ-treated rats ((d–f) and (j–l)). (c), (f), (i), and (l) represent the composite images obtained by overlay of (a)-(b), (d)-(e), (g)-(h), and (j)-(k), respectively. Scale bar = 25 μm.

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