Destabilization of Akt Promotes the Death of Myeloma Cell Lines
Figure 2
Coadministration of Rapa and 17-AAG destabilizes Akt. (a) U266 cells and (b) KM3 cells were treated with vehicle (Ctrl), 20 nmmol/L rapamycin, 600 nmol/L 17-AAG, or rapamycin plus 17-AAG for 48 h. Total Akt expression was measured by immunoblotting. Actin expression served as a loading control. The results shown are representative of three independent experiments.
