Mebeverine for Pediatric Functional Abdominal Pain: A Randomized, Placebo-Controlled Trial
Table 2
Changes in primary and secondary outcome measures.
Mebeverine 59
Placebo 56
value
Change of pain score
Week 4
0.285 0.786*
Week 12
0.151 0.544*
Change of CGI-S
Week 4
0.723 0.630*
Week 12
0.870 0.336*
CGI-I score at week 4
0.057 0.368*
CGI-I score at week 12
0.183 0.634*
Response rate at week 4
24 (54.5) 24 (40.6)
17 (39.5) 30.3
0.117 0.469**
Response rate at week 12
32 (72.7) 32 (54.2)
23 (53.4) 23 (41.0)
0.0503 0.416**
Data are presented as mean ± SD. Data of the intention to treat analysis are shown in . CGI-S, CGI-I: Clinical Global Impression Severity and Improvement Scales. *Mann-Whitney test; **Chi-square test.