Drug Repositioning Discovery for Early- and Late-Stage Non-Small-Cell Lung Cancer

Table 9

IC50 values of potential drugs for early- and late-stage NSCLC.

Effect size	Stage	cMap drug name	MTT	Clonogenic
ES	Early	Mebendazole	<1	>10
		Prenylamine	>5	>10
	Late	Mebendazole	<1	>10
		Spiperone	>10	<10
		Anisomycin	<0.1
		Pyrvinium	<0.1
		Mefloquine	>5
		Niclosamide	>5
value < 0.1	Early	Trichostatin A	<1
		Monensin	<1
		Cloperastine	<10
	Late	Trichostatin A	<1
		Mefloquine	>5
		Pyrvinium	<0.1
		Securinine	>5
		Nortriptyline	<10