Bioassay Directed Isolation and Biological Evaluation of Compounds Isolated from Rubus fairholmianus Gard.

Figure 3

Close view of BRCA2 docked with (a) doxorubicin, (b) tamoxifen (c), 1-(2-hydroxyphenyl)-4-methylpentan-1-one, and (d) 4-methylpentyl benzoate. Isolated compounds (green color ball stick mode) docked with target protein BRCA2 (stick mode) through hydrogen bond interaction (pink color dot).