Research Article
Bioassay Directed Isolation and Biological Evaluation of Compounds Isolated from Rubus fairholmianus Gard.
Table 1
DPPH and ABTS radical scavenging activities of fractions and compounds of R. fairholmianus.
| Fractions and compounds | DPPH radical scavenging activity (IC50: µg/mL) | ABTS radical cation scavenging activity (µM Trolox equivalents/g extract) |
| 1 | 14.73 | 2240.99 ± 32.55 | 2 | 17.95 | 1363.49 ± 23.38 | 3 | 18.70 | 3749.60 ± 5.85 | 4 | 20.31 | 3074.61 ± 35.56 | 5 | 7.16 | 3496.48 ± 51.96 | 6 | 18.01 | 4478.60 ± 35.56 | 7 | 9.55 | 3374.98 ± 23.38 | 8 | 25.56 | 2335.49 ± 40.92 | 9 | 3.61 | 4650.72 ± 15.47 | 10 | 15.36 | 4377.35 ± 11.69 | 11 | 21.97 | 2234.24 ± 5.85 | 12 | 17.61 | 2122.86 ± 32.55 | 13 | 27.79 | 1140.74 ± 30.93 | 14 | 24.63 | 4765.47 ± 47.85 | 15 | 16.39 | 4974.72 ± 45.66 | 16 | 13.41 | 3860.98 ± 42.15 | Compound 1 | 3.23 | 5344.45 ± 24.94 | Compound 2 | 5.09 | 9233.20 ± 54.32a | Compound 3 | 10.76 | 6421.23 ± 84.46d | Compound 4 | 8.57 | 8754.78 ± 42.29b | Compound 5 | 12.35 | 5656.32 ± 38.53 | Compound 6 | 9.43 | 7455.54 ± 62.98c | Butylated hydroxy toluene (BHT) | 13.18 | — | Butylated hydroxy anisole (BHA) | 4.88 | — | Rutin | 5.81 | — | Quercetin | 4.12 | — |
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Values are mean of triplicate determination ± standard deviation. Statistically significant at where a > b > c > d.
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