Impact of Hemodialysis on Dyspnea and Lung Function in End Stage Kidney Disease Patients

Table 2

Body weight, mMRC scale, SBN₂ data (23 patients), and maximum static mouth pressure before and after hemodialysis.

	Before dialysis; 𝑛=25	After dialysis; 𝑛=25	𝑃 value
Body weight (Kg)	74.0 ± 12.0	71.0 ± 12.0	<0.001
BMI (Kg/m^2)	26.0 ± 3.0	25.0 ± 4.0	<0.001
mMRC (acc)	2.0 ± 0.8	0.6 ± 0.7	<0.001
Δ𝑁2/Δ𝑉, % pred.	127.0 ± 25.0	86.0 ± 28.0	<0.001
CC % pred.	90.0 ± 28.0	77.0 ± 22.0	0.03
CV % pred.	125.0 ± 39.0	92.0 ± 41.0	<0.001
FRC % pred.	91 ± 27	88 ± 24	NS
𝑃𝑖max % pred.	70.0 ± 14.0	109.0 ± 15.0	<0.001
𝑃𝑒max % pred.	103.0 ± 24.0	109.0 ± 27.0	NS

Values are mean ± SD obtained in the seated position. Unless otherwise specified, values are expressed as % predicted. Statistical significance for mMRC tested with Wilcoxon’s signed rank test before and after dialysis. Student’s paired 𝑡-test is used for all the other lung function parameters. BMI: body mass index; mMRC: modified medical research council dyspnea scale; 𝑛: number of subjects; Δ𝑁₂/Δ𝑉: slope of phase III; CC: closing capacity; CV: closing volume; FRC: functional residual capacity; 𝑃_𝑖max: maximum static inspiratory pressure; 𝑃_𝑒max: maximum static expiratory pressure.