Sweetening Pharmaceutical Radiochemistry by ¹⁸F-Fluoroglycosylation: A Short Review

Table 1

¹⁸F-Fluoroglycosylated imaging probes and ¹⁹F-fluoroglycosyl derivatives (*) synthesized via CuAAC.

Structure	Target	Reference
	Integrin 𝛼𝑣𝛽3	[19]
	Neurotensin receptor NTS-1	[19]
	None	[21]
	Neurotensin receptor NTS-2*	[22]
	Folate receptor	[23]
	Folate receptor	[24]
	Matrix metalloproteinases MMP-2, MMP-8, MMP-9, and MMP-13*	[25]
	Dopamine receptor D4*	[26]
	Endothelin receptor ETAR	[27]
	Neurotensin receptor NTS-1	[28]
	Epidermal growth factor receptor EGFR	[29]
	Integrin 𝛼𝑣𝛽3	[30]

∗Only the ¹⁹F-compounds were synthesized.