The Soluble Form of CTLA-4 from Serum of Patients with Autoimmune Diseases Regulates T-Cell Responses

Table 1

sCTLA-4 from sera of autoimmune patients is able to interact with its natural ligands.

Patient’s serum	% of inhibition	sCTLA-4 (ng/mL)
55AIT	71	36.40
71AIT	82	73.80
12AIT	58	14.71
37AIT	56	23.04
66AIT	64	47.11
26CD	59	32.18
34CD	84	96.04
101CD	79	53.74
77CD	72	52.76
123CD	77	49.59
1PBC	67	33.63
24PBC	79	43.33
31PBC	62	37.93
41PBC	81	61.44
43PBC	85	81.79
21AIT	0.1	<0.1
44AIT	0.5	<0.1
13CD	0.2	<0.1
97CD	0.3	<0.1
61PBC	0.4	<0.1
69PBC	0.5	<0.1
CTLA-4 Ig	99.9