ECM Inspired Coating of Embroidered 3D Scaffolds Enhances Calvaria Bone Regeneration

Figure 7

Quantification of bone volume within the defect area. (a) Quantification of bone volume related to the entire bone defect area of 13 mm. (b) Representative images of PCL noncoated (top) and PCL coll I/cs coated (bottom) 3-dimensional μCT reconstructions. The left images are marked for visualization and right picture presents the original. The white circles in the left images represent the whole defect area and the yellow circles the 4 mm central part. (c) Quantification of bone formation in the central defect area. Significant differences as indicated: ^∗𝑃<0.05, ^∗∗∗𝑃<0.001 (Student’s 𝑡-test).

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