Exercise Training Could Improve Age-Related Changes in Cerebral Blood Flow and Capillary Vascularity through the Upregulation of VEGF and eNOS

Figure 6

Effect of exercise training on the level of vascular endothelial growth factor (VEGF) in the brain microvessels of sedentary-young (SE-Young), sedentary-aged (SE-Aged), immersed-aged (IM-Aged), and trained-aged (ET-Aged) rats. The VEGF level was significantly lower (𝑃<0.05) in the SE-Aged (20.51±1.75 pg/mg protein) and IM-Aged (19.07±1.27 pg/mg protein) groups compared with the SE-Young group (32.27±0.93 pg/mg protein). The level of VEGF in the ET-Aged (28.35±1.53 pg/mg protein) group was significantly increased when compared with the IM-Aged group (19.07±1.27 pg/mg protein). ^∗𝑃<0.05, significantly different from the SE-Young group. ^#𝑃<0.05, significantly different from the IM-Aged group.