Research Article

Discordant Correlation between Serological Assays Observed When Measuring Heterosubtypic Responses against Avian Influenza H5 and H7 Viruses in Unexposed Individuals

Figure 3

Cross-reactivity antibody profiles of SRH positive human sera against a Group 1 clade 1 H5 and clade 2.1.3.2 H5 and Group 2 H7N1 H7 pseudotypes as measured using pseudotype-based neutralization assays. Antibody response colour chart showing the IC50 neutralizing antibody titres of 68 sera with an SRH titre > 25 mm2 measured against H5 and H7 pseudotypes. Individual end-point titres (as calculated using GraphPad) were split into 9 separate bands based on titre range and assigned an individual colour. Colour legend is reported on the bottom of the figure.
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