Discordant Correlation between Serological Assays Observed When Measuring Heterosubtypic Responses against Avian Influenza H5 and H7 Viruses in Unexposed Individuals
Figure 4
Cross-reactivity antibody profiles of SRH positive human sera against Group 1 H5 (A/Vietnam/1194/04, A/Indonesia/5/05) and H1 (A/SouthCarolina/1/18) and Group 2 H7 (A/chicken/Italy/13474/99) and H3 (A/Udorn/307/72) pseudotypes as measured using pseudotype-based neutralization assays. Antibody response colour chart showing the IC50 neutralizing antibody titres of 37 sera with an SRH titre > 25 mm2 measured against H1, H3, H5, and H7 pseudotypes. Individual end-point titres (as calculated using GraphPad) were split into 9 separate bands based on titre range and assigned an individual colour.
