CD44 Gene Polymorphisms on Hepatocellular Carcinoma Susceptibility and Clinicopathologic Features

Table 5

Association of CD44 genotypic frequencies with HCC laboratory status.

Characteristic	𝛼-Fetoprotein^a (ng/mL)	AST^a (IU/L)	ALT^a (IU/L)	AST/ALT ratio^a
rs1425802
AA	5097.9±2375.8	251.1±61.4	189.7±40.6	1.67±0.22
AG/GG	3799.7±1302.1	154.0±21.6	139.8±21.9	1.46±0.08
𝑃 value	0.602	0.071	0.238	0.268
rs187115
AA	2762.4±1326.1	209.4±39.0	183.2±31.4	1.38±0.08
AG/GG	6530.4±2179.8	153.8±24.7	116.8±15.2	1.76±0.19
𝑃 value	0.119	0.289	0.106	0.077
rs713330
TT	4326.7±1313.1	183.0±29.0	155.3±23.4	1.59±0.11
TC/CC	3879.2±2717.1	208.4±52.8	165.0±31.9	1.26±0.10
𝑃 value	0.885	0.705	0.853	0.169
rs11821102
GG	4866.9±1377.5	200.4±29.5	165.6±22.8	1.56±0.11
GA/AA	674.4±469.4	113.0±29.0	107.3±32.3	1.40±0.12
𝑃 value	0.208	0.226	0.303	0.550
rs10836347
CC	4265.0±1241.4	181.7±24.0	144.8±18.1	1.56±0.10
CT/TT	4108.6±3837.3	232.5±127.4	252.6±106.2	1.27±0.23
𝑃 value	0.967	0.930	0.088	0.317
rs13347
CC	3964.4±1654.2	157.5±36.9	124.1±24.7	1.64±0.16
CT/TT	4582.0±1684.4	223.0±34.7	195.9±32.3	1.40±0.08
𝑃 value	0.795	0.203	0.074	0.201

Mann-Whitney 𝑈 test was used between two groups.
^aMean ± S.E.