CNB-001 a Novel Curcumin Derivative, Guards Dopamine Neurons in MPTP Model of Parkinson’s Disease

<table>Analysis of mitochondrial perimeter length in SN and ST of experimental animals. Mitochondrial perimeter length/mitochondrion was significantly more increased in MPTP group than in control. Pretreatment with CNB-001 significantly maintained mitochondrial size as compared to MPTP group. No significant changes were observed in control and CNB-001 treated groups. <svg height="17.825001" id="M29" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 69.150002 17.825001" width="69.150002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared to control, <svg height="19.65" id="M30" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 70.224998 19.65" width="70.224998" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared to MPTP.</table>

BioMed Research International

fig9

Figure 9

Figure 9: CNB-001 a Novel Curcumin Derivative, Guards Dopamine Neurons in MPTP Model of Parkinson’s Disease 