MicroRNA Dysregulation in Liver and Pancreas of CMP-Neu5Ac Hydroxylase Null Mice Disrupts Insulin/PI3K-AKT Signaling

Table 2

KEGG pathway analysis of miRNA target genes.

miRNAs	Significant pathway	value	Target genes
miR-155-5p,; miR-15a-5p,; miR-425-5p	Insulin; signaling; pathway	0.0339	Rheb, Socs1, Pik3r1, Eif4e2, Prkar2a, Prkx, Crkl, Sos1, Bad, Acaca, Pik3r3, Fasn, Exoc7, Mapk3, Flot2, Raf1, Mtor
miR-503-5p,; miR-15a-5p,; miR-16-5p,; miR-29b-3p,; miR-29a-3p	PI3K-Akt signaling; pathway	0.0060	Pik3r1, Prkar2a, Sos1, Pik3r3, Fasn, Exoc7, Mapk3, Flot2, Raf1, Mtor, Col3a1, Col1a1, Col5a3, Bcl2l11, COl4a2, Cdkn1b, Ccnd2, Bcl2