Pharmacological Strategies to Prevent Contrast-Induced Acute Kidney Injury

Table 1

Meta-analysis comparing the efficacy of sodium bicarbonate and sodium chloride for contrast-induced AKI prophylaxis.

References		Number of patients	Number of trials	RR	95% CI		𝑃 value
Authors	Year				Low	High
Hogan et al. [38]	2008	1,307	7	0.37	0.18	0.714	0.005
Kanbay et al. [39]	2009	2,448	17	0.54	0.36	0.83	ND
Navaneethan et al. [40]	2009	1,652	12	0.46	0.26	0.82	0.008
Zoungas et al. [41]	2009
(i) Published studies		1,846	9	0.43	0.25	0.75	0.02
(ii) Unpublished studies		1,717	14	0.78	0.52	1.17	0.05
Kunadian et al. [42]	2011	1,734	7	0.33	0.16	0.69	0.003
Jang et al. [37]	2012	3,609	19	0.56	0.36	0.86	0.008