Research Article
Identification of Influenza A/H7N9 Virus Infection-Related Human Genes Based on Shortest Paths in a Virus-Human Protein Interaction Network
Table 2
The infection-related human proteins and their related coding genes for the three species of viruses calculated from shortest paths in a PPI network.
| | Infected by virus | Protein | Gene | Chromosome | Betweenness |
| | Influenza A/H7N9 | ENSP00000361626 | YBX1 | 1 | 58376 | | ENSP00000363676 | RPL11 | 1 | 49155 | | ENSP00000396127 | RAN | 12 | 49036 | | ENSP00000362413 | PGK1 | X | 26743 | | ENSP00000229239 | GAPDH | 12 | 25345 | | ENSP00000294172 | NXF1 | 11 | 23550 | | ENSP00000352400 | NUP214 | 9 | 21849 | | ENSP00000280892 | EIF4E | 4 | 20883 | | ENSP00000379933 | TPI1 | 12 | 19217 | | ENSP00000348877 | GPI | 19 | 18885 | | ENSP00000317904 | GYS1 | 19 | 18349 | | ENSP00000350283 | BRCA1 | 17 | 16827 | | ENSP00000283195 | RANBP2 | 2 | 16823 | | ENSP00000400591 | SNRPE | 1 | 15796 | | ENSP00000265686 | TCIRG1 | 11 | 14465 | | ENSP00000358563 | DKC1 | X | 13535 | | ENSP00000234396 | ATP6V1B1 | 2 | 13432 | | ENSP00000218516 | GLA | X | 12471 | | ENSP00000262030 | ATP5B | 12 | 11891 | | ENSP00000260947 | BARD1 | 2 | 11297 |
| | Human Rhinovirus (HRV) | ENSP00000344818 | UBC | 12 | 330154 | | ENSP00000363676 | RPL11 | 1 | 154993 | | ENSP00000361626 | YBX1 | 1 | 136548 | | ENSP00000357879 | PSMD4 | 1 | 121991 | | ENSP00000337825 | LCK | 1 | 117195 | | ENSP00000396127 | RAN | 12 | 116059 | | ENSP00000348461 | RAC1 | 7 | 111632 | | ENSP00000230354 | TBP | 6 | 100485 | | ENSP00000350283 | BRCA1 | 17 | 65076 | | ENSP00000314949 | POLR2A | 17 | 54470 | | ENSP00000280892 | EIF4E | 4 | 50359 |
| | Respiratory syncytial virus (RSV) | ENSP00000269305 | TP53 | 17 | 15809765 | | ENSP00000344456 | CTNNB1 | 3 | 5756301 | | ENSP00000263253 | EP300 | 22 | 5694027 | | ENSP00000339007 | GRB2 | 17 | 5591895 | | ENSP00000275493 | EGFR | 7 | 5245421 | | ENSP00000270202 | AKT1 | 14 | 4663263 | | ENSP00000264657 | STAT3 | 17 | 4180564 | | ENSP00000350941 | SRC | 20 | 3180369 | | ENSP00000348461 | RAC1 | 7 | 3066312 | | ENSP00000221494 | SF3A2 | 19 | 2994393 | | ENSP00000417281 | MDM2 | 12 | 2686189 | | ENSP00000338345 | SNCA | 4 | 2647616 | | ENSP00000206249 | ESR1 | 6 | 2643164 | | ENSP00000296271 | RHO | 3 | 2573058 | | ENSP00000329623 | BCL2 | 18 | 2541856 | | ENSP00000376609 | GRK5 | 10 | 2364221 | | ENSP00000337825 | LCK | 1 | 2306232 | | ENSP00000314458 | CDC42 | 1 | 2174421 | | ENSP00000262613 | SLC9A3R1 | 17 | 2097178 | | ENSP00000355865 | PARK2 | 6 | 2033100 | | ENSP00000264033 | CBL | 11 | 1930392 | | ENSP00000269571 | ERBB2 | 17 | 1922027 | | ENSP00000338018 | HIF1A | 14 | 1915325 | | ENSP00000324806 | GSK3B | 3 | 1910676 | | ENSP00000215832 | MAPK1 | 22 | 1831541 | | ENSP00000358490 | CD2 | 1 | 1751073 | | ENSP00000262160 | SMAD2 | 18 | 1727787 | | ENSP00000304903 | CD2BP2 | 16 | 1714523 | | ENSP00000362649 | HDAC1 | 1 | 1703720 | | ENSP00000353483 | MAPK8 | 10 | 1702626 | | ENSP00000261799 | PDGFRB | 5 | 1679113 | | ENSP00000003084 | CFTR | 7 | 1662248 | | ENSP00000401303 | SHC1 | 1 | 1548773 | | ENSP00000321656 | CDC25C | 5 | 1521621 | | ENSP00000357656 | FYN | 6 | 1503978 | | ENSP00000326366 | PSEN1 | 14 | 1498004 | | ENSP00000230354 | TBP | 6 | 1458835 | | ENSP00000300093 | PLK1 | 16 | 1444680 | | ENSP00000350283 | BRCA1 | 17 | 1389799 | | ENSP00000228307 | PXN | 12 | 1358706 | | ENSP00000329357 | SP1 | 12 | 1347630 | | ENSP00000361626 | YBX1 | 1 | 1342956 | | ENSP00000387662 | GCG | 2 | 1321174 | | ENSP00000367207 | MYC | 8 | 1284185 |
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