Hepatoprotective and Antioxidant Effect of Bauhinia hookeri Extract against Carbon Tetrachloride-Induced Hepatotoxicity in Mice and Characterization of Its Bioactive Compounds by HPLC-PDA-ESI-MS/MS

Table 2

Effect of BHE on hepatic marker enzymes after 6 weeks of CCl₄ intoxication in mice.

Animal groups	ALT (U/L)	AST (U/L)	ALP (IU/L)
Control	13.23 ± 0.71^$	122.40 ± 2.68^$	81.06 ± 4.73^$
CCl4	43.25 ± 3.05*	223.30 ± 5.32*	143.65 ± 3.82*
BHE (500 mg/kg/day)	24.29 ± 2.60^#; (44%)	142.84 ± 5.45^#; (36%)	104.14 ± 5.44^#; (28%)
BHE (1000 mg/kg/day)	15.76 ± 2.72^$#; (64%)	120.24 ± 5.83^$; (46%)	83.76 ± 5.86^$#; (42%)
Silymarin; (500 mg/kg/day)	23.64 ± 2.25^#; (45%)	125.06±3.43^$#; (44%)	89.78 ± 5.24^$#; (38%)

Data are expressed as the means ± SEM, (𝑛=9).
The numbers in parentheses represent the percentage of reduction from the CCl₄-intoxicated group.
Values having different superscripts within the same column are significantly different at 𝑃<0.05.