Advance in ERG Analysis: From Peak Time and Amplitude to Frequency, Power, and Energy

Figure 5

20 consecutive single-flash ERG responses (gray traces) obtained from a patient affected with retinitis pigmentosa. The average of these 20 raw ERG responses canceled the uncorrelated noise to yield the blue tracing (overlaid on top of each single-flash response). DWT denoising of the individual noisy single-flash responses reveals denoised biological responses, which are shown as red traces. All red traces are nearly identical (shape and amplitude) to the trace obtained from the average (i.e., blue traces) of the 20 noisy responses, thus validating this denoising approach. The horizontal (time) and vertical (voltage) scale bars apply to each trace. The flash onset is indicated by the black vertical arrow.