Endothelium-Independent Vasorelaxant Effects of Hydroalcoholic Extract from Nigella sativa Seed in Rat Aorta: The Roles of Ca²⁺ and K⁺ Channels

Figure 1

Effect of different concentrations of Nigella sativa extract (2, 4, 6, 8, 10, and 14 mg/mL) on PE (10⁻⁶  M) (a) and KCl (6×10⁻²  M) (b) precontracted rat aortic rings with (+E) or without (−E) endothelium. Data are expressed as mean ± S.E.M. (𝑛=8). ^∗∗∗𝑃<0.001, ^∗∗𝑃<0.01 compared to base.

(a)

(b)