Development and Evaluation of an Open-Source Software Package “CGITA” for Quantifying Tumor Heterogeneity with Molecular Images

Table 2

Summary of the software features of CGITA.

Feature	CGITA implementation
Programming environment	MATLAB (MathWorks Inc.)
License	Free for academic use
Source code availability	Open source
Supported image format	DICOM (either local files or direct access to a PACS server for image retrieval)
Supported VOI format	DICOM-RT, PMOD
Currently supported textural features	72
Other features	(i) Parametric imaging of heterogeneity indices; (ii) Batch mode for processing a large cohort; (iii) Compiled stand-alone application available; (iv) Supporting user-defined functions for heterogeneity calculation