Neuromodulatory Effects of Hesperidin in Mitigating Oxidative Stress in Streptozotocin Induced Diabetes

<table>Effect of HP treatment on (a) NP-SH and (b) GSH level in rat brain. Each value is represented as mean ± SE (<svg height="11.225" id="M14" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 36.237499 11.225" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>). NP-SH and GSH was significantly decreased in (<svg height="17.825001" id="M15" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 76.137497 17.825001" width="76.137497" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>) STZ group rats as compared to control group. HP treatment has significantly (<svg height="19.65" id="M17" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 70.224998 19.65" width="70.224998" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>) increased the level of NP-SH and GSH in STZ + HP group as compared to STZ group rats. Each value is represented as mean ± SE (<svg height="11.225" id="M19" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 36.237499 11.225" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>).</table>

BioMed Research International

fig2

Figure 2

Figure 2: Neuromodulatory Effects of Hesperidin in Mitigating Oxidative Stress in Streptozotocin Induced Diabetes 