Neuromodulatory Effects of Hesperidin in Mitigating Oxidative Stress in Streptozotocin Induced Diabetes
Figure 3
STZ induced significant ( and ) alterations in the activities of antioxidant enzymes, (a) GST, (b) GR, and (c) XO, in the STZ group rats when compared with the control group rats. HP treatment protected the activity of (a) GST and (b) GR in rat brain. Administration of HP has significantly attenuated the activity of GST and GR () in the STZ + HP group rats as compared with the STZ group rats. The activity of XO was significantly () increased in STZ group as compared to control group rats. Administration of HP has significantly () lowered the activity of XO in the STZ + HP group rats as compared with the STZ group rats. Each value is represented as mean ± SE ().
