Neuromodulatory Effects of Hesperidin in Mitigating Oxidative Stress in Streptozotocin Induced Diabetes

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</svg>) alteration was observed in the activity of neurotoxicity marker enzymes (a) AChE and (b) Na<sup>+</sup>/K<sup>+</sup>-ATPase in the STZ group rats as compared with the control group. Administration of HP has significantly (<svg height="19.65" id="M35" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 70.224998 19.65" width="70.224998" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>) attenuated the activity of these enzymes in the STZ + HP group rats as compared with STZ group rats. No significant changes in the activity of (c) MAO in STZ as well as STZ + HP group rats were observed in the rat brain. Each value is represented as mean ± SE (<svg height="11.225" id="M37" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 36.237499 11.225" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>).</table>

BioMed Research International

fig4

Figure 4

Figure 4: Neuromodulatory Effects of Hesperidin in Mitigating Oxidative Stress in Streptozotocin Induced Diabetes 