Research Article
Pu-Erh Tea Extract Induces the Degradation of FET Family Proteins Involved in the Pathogenesis of Amyotrophic Lateral Sclerosis
Table 2
Identification of the PTE binding protein based on peptide fragments produced by MAILDI-TOF MS.
| Peptide | Start–end | Observed | Mr (expt.) | Mr (calc.) | Delta |
|
K.KTGQPMINLYTDR.E | 90–102 | 1536.7841 | 1535.7768 | 1535.7766 | 0.0002 | K.KTGQPMINLYTDR.E + oxidation (M) | 90–102 | 1552.7707 | 1551.7635 | 1551.7715 | −0.0080 | K.TGQPMINLYTDR.E | 90–102 | 1408.7088 | 1407.7015 | 1407.6816 | 0.0199 | K.TGQPMINLYTDRETGK.L | 91–106 | 1823.8919 | 1822.8847 | 1822.8883 | −0.0037 | K.LKGEATVSFDDPPSAK.A | 107–122 | 1661.8517 | 1660.8444 | 1660.8308 | 0.0136 | K.AAIDWFDGKEFSGNPIK.V | 123–139 | 1894.9324 | 1893.9251 | 1893.9261 | −0.0010 | K.CPNPTCENMNFSWP.N | 202–215 | 1698.6680 | 1697.6608 | 1697.6749 | −0.0141 | K.APKPDGPGGGPGGSHMGGNYGDDR.R | 223–246 | 2252.9478 | 2251.9406 | 2251.9665 | −0.0259 | NCBI database | | GI:62087384 | | | |
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