Research Article
Association between Oxidative Stress and Outcome in Different Subtypes of Acute Ischemic Stroke
Table 2
Prognostic factors in patients with acute ischemic stroke.
| | | Good outcome
(n = 80) | Poor outcome
(n = 20) | Crude OR
(95% CI) | P value | Adjusted OR
(95% CI) | P value |
| | Age (year) | 61.2 ± 11.5 | 65.1 ± 8.0 | 1.04 (0.99–1.09) | 0.16 | — | — | | Sex (male) (n) | 62 | 15 | 0.87 (0.28–2.72) | 0.81 | — | — | | Hypertension (n) | 61 | 17 | 1.77 (0.47–6.68) | 0.55 | — | — | | Diabetes mellitus (n) | 32 | 10 | 1.50 (0.56–4.01) | 0.46 | — | — | | Hyperlipidemia (n) | 38 | 11 | 1.35 (0.51–3.61) | 0.62 | — | — | | Cardiac disease (n) | 5 | 2 | 1.67 (0.30–9.30) | 0.80 | — | — | | NIHSS score on admission | | | 1.35 (1.16–1.58) | <0.001 | 1.55 (1.11–2.16) | 0.01 | | Stroke subtype (large/small) | | | 21.0 (6.26–70.4) | <0.001 | 0.01 (0.001–0.33) | 0.008 | | Small vessel disease | 70 | 5 | | | — | — | | Large vessel disease | 10 | 15 | | | — | — | | With statin therapy | 35 | 11 | 1.49 (0.56–4.00) | 0.46 | — | — | | Laboratory data on admission | | | | | — | — | | White blood cells (×103/mL) | 7.4 ± 0.2 | 8.3 ± 0.6 | 1.17 (0.96–1.43) | 0.12 | — | — | | Hemoglobin (g/dL) | 13.8 ± 0.2 | 13.6 ± 0.3 | 0.91 (0.69–1.22) | 0.53 | | | | Red blood cells (×106/mL) | 4.8 ± 0.1 | 4.5 ± 0.1 | 0.50 (0.24–1.07) | 0.07 | — | — | | Platelet counts (×104/mL) | 21.2 ± 0.6 | 18.9 ± 1.4 | 0.99 (0.98–1.00) | 0.12 | — | — | | Total cholesterol (mg/dL) | 185.7 ± 4.6 | 180.0 ± 8.6 | 0.99 (0.98–1.01) | 0.58 | — | — | | LDL-cholesterol (mg/dL) | 114.2 ± 4.2 | 109.6 ± 7.7 | 0.99 (0.98–1.01) | 0.62 | — | — | | HDL-cholesterol (mg/dL) | 43.8 ± 1.0 | 45.6 ± 3.0 | 1.02 (0.97–1.07) | 0.48 | — | — | | Triglyceride (mg/dL) | 136.3 ± 7.6 | 128.3 ± 13.8 | 0.99 (0.99–1.01) | 0.63 | — | — | | HbA1c (%) | 6.8 ± 0.2 | 7.3 ± 0.6 | 1.14 (0.90–1.45) | 0.28 | — | — | | Systolic BP (mmHg) | 147.1 ± 2.8 | 140.1 ± 4.4 | 0.99 (0.97–1.01) | 0.28 | — | — | | Diastolic BP (mmHg) | 84.5 ± 1.5 | 81.1 ± 2.8 | 0.98 (0.94–1.02) | 0.31 | — | — | | Free thiol on admission (μM/L) | 0.92 ± 0.03 | 0.70 ± 0.07 | 0.04 (0.01–0.32) | 0.002 | — | — | | TBARS on admission (μM/L) | 19.9 ± 0.72 | 24.1 ± 3.0 | 1.05 (0.99–1.11) | 0.06 | — | — | | Free thiol on day 7 (μM/L) | 0.96 ± 0.04 | 0.66 ± 0.08 | 0.12 (0.03–0.52) | 0.005 | — | — | | TBARS on day 7 (μM/L) | 18.4 ± 0.77 | 29.1 ± 2.8 | 1.14 (1.07–1.22) | <0.001 | 1.37 (1.14–1.65) | 0.001 | | Free thiol on day 30 (μM/L) | 1.00 ± 0.04 | 0.88 ± 0.11 | 0.29 (0.05–1.75) | 0.78 | — | — | | TBARS on day 30 (μM/L) | 19.7 ± 1.24 | 20.4 ± 2.4 | 1.01 (0.95–1.07) | 0.82 | — | — |
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Abbreviations: BP: blood pressure; HbA1c: hemoglobin A1c.
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