Table 1: Summary of addictive drugs, their targets, and classification.

DrugBank IDDrug name Number of targetsDrugBank groupNIDA categorya

DB00316Acetaminophen2ApprovedOpioids and morphine derivatives
DB00404Alprazolam20Approved, illicitDepressants
DB01351Amobarbital10Approved, illicitDepressants
DB00182Amphetamine4Approved, illicitStimulants
DB01541Boldenone1Experimental, illicitOther compounds
DB00475Chlordiazepoxide19Approved, illicitDepressants
DB00907Cocaine8Approved, illicitStimulants
DB00318Codeine3Approved, illicitOpioids and morphine derivatives
DB01189Desflurane7ApprovedOther compounds
DB00514Dextromethorphan4ApprovedOther compounds
DB00829Diazepam18Approved, illicitDepressants
DB00228Enflurane8ApprovedOther compounds
DB00898Ethanol7ApprovedOther compounds
DB00813Fentanyl3Approved, illicitOpioids and morphine derivatives
DB01544Flunitrazepam6Approved, illicitDepressants
DB01440Gamma hydroxybutyric acid1Approved, illicitDepressants
DB01159Halothane17ApprovedOther compounds
DB01452Heroin3Approved, illicitOpioids and morphine derivatives
DB00956Hydrocodone2Approved, illicitOpioids and morphine derivatives
DB00327Hydromorphone3Approved, illicitOpioids and morphine derivatives
DB00753Isoflurane7ApprovedOther compounds
DB01221Ketamine3ApprovedDissociative anesthetics
DB00186Lorazepam20ApprovedDepressants
DB04829Lysergic acid diethylamide0Illicit, withdrawnHallucinogens
DB00454Meperidine6ApprovedOpioids and morphine derivatives
DB01577Methamphetamine11Approved, illicitStimulants
DB04833Methaqualone0Illicit, withdrawnDepressants
DB01028Methoxyflurane7ApprovedOther compounds
DB00422Methylphenidate3Approved, investigationalStimulants
DB01442MMDA8Experimental, illicitStimulants
DB00295Morphine3ApprovedOpioids and morphine derivatives
DB00486Nabilone2ApprovedOther compounds
DB00984Nandrolone phenpropionate0Approved, illicitOther compounds
DB00184Nicotine11ApprovedStimulants
DB00621Oxandrolone1ApprovedOther compounds
DB00497Oxycodone3Approved, illicitOpioids and morphine derivatives
DB00312Pentobarbital10ApprovedDepressants
DB03575Phencyclidine2Experimental, illicitDissociative anesthetics
DB01174Phenobarbital10ApprovedDepressants
DB00647Propoxyphene3Approved, illicitOpioids and morphine derivatives
DB00418Secobarbital10ApprovedDepressants
DB01236Sevoflurane7ApprovedOther compounds
DB00624Testosterone1ApprovedOther compounds
DB00897Triazolam20Approved, illicit, withdrawnDepressants

Drug category is defined based on the similarities regarding how drugs function and what effects they produce in the human body, including the brain, as annotated by NIDA.