Gastric Antiulcerogenic and Hypokinetic Activities of Terminalia fagifolia Mart. & Zucc. (Combretaceae)

Table 3

Effect of the intraduodenal administration of the Terminalia fagifolia ethanolic bark extract (TFEE) and ranitidine on pH and total acidity of gastric secretion and gastric juice volume and on the gastric wall mucus or nonprotein sulfhydryl group contents in four-hour pylorus ligated rats.

Parameter	Vehicle; (5 mL/kg)	TFEE; (500 mg/kg)	Ranitidine; (60 mg/kg)
pH (units)	2.22±0.07	3.76±0.39^∗	5.80±0.66^∗
Volume (mL)	3.02±0.17	1.18±0.21^∗	1.48±0.22^∗
Total acidity (𝜇Eq/h)	69.77±5.51	13.19±4.33^∗	5.83±3.13^∗
Gastric wall mucus (𝜇g/g)	36.07±4.42	34.47±2.83	38.97±2.32
Nonprotein SH (𝜇M/g)	48.17±1.80	46.11±2.45	42.44±3.37

The data represent the mean ± S.E.M. of groups of 6–8 animals. *𝑃<0.05 (ANOVA and Dunnett’s test) compared to the respective control group.