Research Article
Recognition of 27-Class Protein Folds by Adding the Interaction of Segments and Motif Information
Table 1
Datasets of 27-class protein folds.
| Fold | Dataset built by Liu et al. [27] |
Dataset built by Ding and Dubchak [11] | Training set | Testing set | Training set | Testing set |
| All structural class | 174 | 169 | 54 | 61 | (1) Globin-like | 14 | 14 | 13 | 6 | (2) Cytochrome c | 10 | 10 | 7 | 9 | (3) DNA-binding 3-helical bundle | 92 | 90 | 12 | 20 | (4) 4-helical up-and-down bundle | 25 | 24 | 7 | 8 | (5) 4-helical cytokines | 8 | 8 | 9 | 9 | (6) Alpha; EF-hand | 25 | 23 | 6 | 9 | All β structural classes | 260 | 254 | 109 | 117 | (7) Immunoglobulin-like β-sandwich | 86 | 85 | 30 | 44 | (8) Cupredoxins | 18 | 18 | 9 | 12 | (9) Viral coat and capsid proteins | 24 | 24 | 16 | 13 | (10) ConA-like lectins/glucanases | 18 | 17 | 7 | 6 | (11) SH3-like barrel | 41 | 41 | 8 | 8 | (12) OB-fold | 29 | 28 | 13 | 19 | (13) Trefoil | 11 | 10 | 8 | 4 | (14) Trypsin-like serine proteases | 17 | 16 | 9 | 4 | (15) Lipocalins | 16 | 15 | 9 | 7 | /β structural class | 341 | 337 | 115 | 143 | (16) (TIM)-barrel | 93 | 92 | 29 | 48 | (17) FAD (also NAD)-binding motif | 5 | 5 | 11 | 12 | (18) Flavodoxin-like | 37 | 36 | 11 | 13 | (19) NAD(P)-binding Rossmann-fold | 17 | 16 | 13 | 27 | (20) P-loop-containing nucleotide | 74 | 73 | 10 | 12 | (21) Thioredoxin-like | 37 | 36 | 9 | 8 | (22) Ribonuclease H-like motif | 39 | 40 | 10 | 12 | (23) Hydrolases | 33 | 33 | 11 | 7 | (24) Periplasmic binding protein-like | 6 | 6 | 11 | 4 | + β structural class | 181 | 179 | 33 | 62 | (25) β-Grasp | 39 | 39 | 7 | 8 | (26) Ferredoxin-like | 101 | 99 | 13 | 27 | (27) Small inhibitors, toxins, and lectins | 41 | 41 | 13 | 27 |
| Overall | 956 | 939 | 311 | 383 |
|
|