Magnesium Lithospermate B, an Active Extract of Salvia miltiorrhiza, Mediates sGC/cGMP/PKG Translocation in Experimental Vasospasm

Figure 4

Suppressed PKC𝛿 translocation by MLB in the BAs. The bio-expression of PKC𝛿 from the cytoplasm to membrane was determined by Western blot analysis. The ratio of membrane bound to cytoplasm PKC𝛿 in the SAH group was set at 100%. Data are shown as mean ± SEM (𝑛=9/group). ^∗,∗∗𝑃<0.01, the vehicle +SAH versus Sham and MLB prevention groups, respectively, and ^#𝑃>0.05: compared with SAH rats pre-treatment with MLB and L-NAME. All groups are identical to those shown in the legend of Figure 2.