WISCOD: A Statistical Web-Enabled Tool for the Identification of Significant Protein Coding Regions

Table 1

The capacity to detect real exons from a large list of potential exons taking account of different levels of confidence (EPFE values) in a HAVANA subset of manual curated genes on HSA21.

transcripts = 116		Mean			Med.			q25			q75
potential exons (total)		26649.59			10790.00			3870.50			33168.00
real exons (total)		9.23			7.00			3.00			13.00
% real enrichment		0.11			0.08			0.03			0.14
	EPFE	CHI-S				LOGIT				GAUSSIAN
		Mean	Med.	q25	q75	Mean	Med.	q25	q75	Mean	Med.	q25	q75
potential exons		39	27	9	55	68	46	17	89	110	77	23	141
% real exons	<0.001	53.9	61.3	33.3	80.0	64.7	72.7	50.0	91.8	70.1	85.7	50.0	100
% real enrichment		16.9	16.3	6.0	22.4	12.0	11.1	4.4	14.6	8.5	7.8	3.2	11.6
potential exons		300	201	58	376	387	252	75	483	473	305	88	587
% real exons	<0.005	79.6	96.2	82.5	100	81.4	100	83.3	100	81.9	100	82.5	100
% real enrichment		3.9	3.4	1.3	5.9	3.1	2.6	1.0	4.4	2.7	2.4	0.8	3.8
potential exons		604	369	105	725	788	493	134	918	857	537	143	1002
% real exons	<0.01	84.9	100	87.1	100	85.5	100	88.9	100	86.3	100.0	90.7	100
% real enrichment		2.2	1.9	0.7	3.1	1.8	1.5	0.6	2.6	1.7	1.5	0.6	2.5
potential exons		1291	774	206	1465	1511	852	240	1697	1596	887	252	1795
% real exons	<0.02	89.3	100	100	100	90.5	100	100	100	89.4	100	100	100
% real enrichment		1.2	1.0	0.4	1.7	1.1	1.0	0.3	1.6	1.0	0.9	0.3	1.5