Neuroprotective Effects of Geniposide in SH-SY5Y Cells and Primary Hippocampal Neurons Exposed to Aβ42

Figure 6

Preincubation of geniposide with Aβ inhibiting the formation of β-sheet in Aβ. Amyloid β was incubated with TLJN or its ingredients (geniposide∖ginsenoside Rg1) at 37°C for 24 h, and Aβ fibrillogenesis was measured with ThT fluorescence (450 nm) (a). Geniposide at different concentrations was incubated with Aβ, followed by measurement of the fluorescent intensity of ThT at different time intervals (b). Data were represented as mean standard deviation (SD), ^*, ^**.

(a)

(b)