A Systematic Analysis of miRNA-mRNA Paired Variations Reveals Widespread miRNA Misregulation in Breast Cancer

<table class="table-group" id="tab4"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td align="left">Feature</td><td align="center">Average degree</td><td align="center"><svg height="11.175" id="M9" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 10.9375 11.175" width="10.9375" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> value</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td align="left">ER</td><td align="center">11.76</td><td align="center">0.03</td></tr><tr><td align="left">TP53</td><td align="center">11.23</td><td align="center"><b>0.01</b></td></tr><tr><td align="left">HER2</td><td align="center">11.74</td><td align="center"><span style="width: 75.362503px;"><svg height="12.0625" id="M10" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 75.362503 12.0625" width="75.362503" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg></span></td></tr><tr><td align="left">Survival</td><td align="center">12.81</td><td align="center"><span style="width: 54.5px;"><svg height="12.0625" id="M11" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 54.5 12.0625" width="54.5" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg></span></td></tr><tr><td align="left">Subtype</td><td align="center">10.60</td><td align="center">0.095</td></tr><tr><td align="left">HPRD-PPI network</td><td align="center">7.80</td><td align="center"> </td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Comparison of the average degree of the different types of MPPVs with that in the HPRD-PPI network.

BioMed Research International

tab4

Table 4

Table 4: A Systematic Analysis of miRNA-mRNA Paired Variations Reveals Widespread miRNA Misregulation in Breast Cancer 