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Model | Experimental conditions | Methodology** | References |
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MDR strains | 1 | Comparison between MDR and H37Rv strains | MA | Chatterjee et al. (2013) [32] |
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Toxic substances (in vitro) | 2 | SDS | RT-qPCR and MA | Manganelli et al. (2001) [33] |
3 | Isoniazid, isoxyl, tetrahydrolipstatin, SRI #221, SRI #967, and SRI #9190 | MA | Waddell et al. (2004) [34] |
4 | Sodium hypochlorite | MA | Jang et al. (2009) [35] |
5 | Peracetic acid | MA | Nde et al., (2011) [36] |
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Toxic substances related to infection (in vitro) | 6 | Oxidative stress | MA | Manganelli et al. (2002) [37] |
7 | Nitrogen reactive substances | RT-qPCR and MA | Ohno et al. (2003) [38] |
8 | Physiological levels of copper | RT-qPCR | Ward et al. (2008) [39] |
9 | Physiological levels of zinc | RT-qPCR and MA | Botella et al. (2011) [11] |
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Latency (in vitro) | 10 | Hypoxia | MA | Sherman et al. (2001) [40] |
11 | Hypoxia | MA | Bacon et al. (2004) [41] |
12 | Hypoxia and nitric oxide | MA | Voskuil et al. (2003) [42] |
13 | Steady culture | RT-qPCR and MA | Kendall et al. (2004) [43] |
14 | Nonreplicating persistence (NRP) | MA | Muttucumaru et al. (2004) [44] |
15 | Nonreplicating persistence (NRP) | Proteomic | Cho et al. (2006) [13] |
16 | Starvation | MA | Hampshire et al. (2004) [45] |
17 | Starvation | MA | Betts et al. (2002) [46] |
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Infection (in vivo) | 18 | Mouse macrophage infection | MA | Schnappinger et al. (2003) [47] |
19 | Mouse lung infection | MA | Talaat et al. (2004) [31] |
20 | Artificial granulomas in mice | MA | Karakousis et al. (2004) [48] |
21 | Human dendritic cells and macrophage infection | MA | Tailleux et al. (2008) [49] |
22 | Human lung infection | RT-qPCR | Kumar et al. (2011) [50] |
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