Research Article

Body Pigmentation as a Risk Factor for the Formation of Intracranial Aneurysms

Table 3

Results of logistic regression in Sample II.

Explanatory variablesPatients
(%)
Controls
(%)
Adjusted odds ratio
(95% CI)
  

Sample II5838

Hair color
 Dark brown to brown12 (20.7)25 (65.8)1.000.001 (8.10)
 Light brown to dark blond23 (39.7)10 (26.3)2.36 (0.44–12.78)
 Blond to strawberry blonde/red23 (39.6)3 (7.9)29.11*** (3.78–224.32)
Eye color
 Dark color14 (24.1)13 (34.2)1.000.58 (0.09)
 Mixed color17 (29.3)6 (15.8)2.06 (0.30–14.19)
 Light color27 (46.6)19 (50.0)1.70 (0.35–8.32)
Skin color
 Dark15 (25.9)17 (44.7)1.000.68 (0.02)
 Medium19 (32.8)13 (34.2)1.43 (0.30–6.82)
 Light24 (41.3)8 (21.1)1.43 (0.28–7.41)
Skin phototype
 Rarely/never burns, tans profusely (V + VI)6 (10.3)22 (57.9)1.000.04 (0.48)
 Burns moderately/minimally, tans moderately (III + IV)19 (32.8)12 (31.6)2.08 (0.43–10.05)
 Burns easily, tans never/minimally (I + II)33 (56.9)4 (10.5)6.08* (1.11–33.45)
Handedness
 Pronounced right-handed8 (14.0)24 (63.2)1.000.001 (11.40)
 Moderate right-handed20 (35.1)11 (28.9)22.36** (2.64–189.32)
 Bimanual or left-handed29 (50.9)3 (7.9)64.09*** (5.40–760.69)

Odds ratios were adjusted for age, sex, and smoking ( values for these covariates were 0.001, 0.009, and 0.558, resp.); for trend; explained variance (%) by the respective variable (Nagelkerke +); *significance for odds ratios: * , ** , and *** .