Body Pigmentation as a Risk Factor for the Formation of Intracranial Aneurysms
Table 3
Results of logistic regression in Sample II.
Explanatory variables
Patients (%)
Controls (%)
Adjusted odds ratio† (95% CI)
Sample II
58
38
Hair color
Dark brown to brown
12 (20.7)
25 (65.8)
1.00
0.001 (8.10)
Light brown to dark blond
23 (39.7)
10 (26.3)
2.36 (0.44–12.78)
Blond to strawberry blonde/red
23 (39.6)
3 (7.9)
29.11*** (3.78–224.32)
Eye color
Dark color
14 (24.1)
13 (34.2)
1.00
0.58 (0.09)
Mixed color
17 (29.3)
6 (15.8)
2.06 (0.30–14.19)
Light color
27 (46.6)
19 (50.0)
1.70 (0.35–8.32)
Skin color
Dark
15 (25.9)
17 (44.7)
1.00
0.68 (0.02)
Medium
19 (32.8)
13 (34.2)
1.43 (0.30–6.82)
Light
24 (41.3)
8 (21.1)
1.43 (0.28–7.41)
Skin phototype
Rarely/never burns, tans profusely (V + VI)
6 (10.3)
22 (57.9)
1.00
0.04 (0.48)
Burns moderately/minimally, tans moderately (III + IV)
19 (32.8)
12 (31.6)
2.08 (0.43–10.05)
Burns easily, tans never/minimally (I + II)
33 (56.9)
4 (10.5)
6.08* (1.11–33.45)
Handedness
Pronounced right-handed
8 (14.0)
24 (63.2)
1.00
0.001 (11.40)
Moderate right-handed
20 (35.1)
11 (28.9)
22.36** (2.64–189.32)
Bimanual or left-handed
29 (50.9)
3 (7.9)
64.09*** (5.40–760.69)
Odds ratios were adjusted for age, sex, and smoking ( values for these covariates were 0.001, 0.009, and 0.558, resp.); for trend; explained variance (%) by the respective variable (Nagelkerke +); *significance for odds ratios: *, **, and ***.