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BioMed Research International
Volume 2014 (2014), Article ID 302747, 4 pages
Clinical Study

Investigation of the Effects of Preoperative Hydration on the Postoperative Nausea and Vomiting

1Duatepe Polatlı State Hospital, Ankara, Turkey
2Türkiye Yüksek İhtisas Education and Research Hospital, Anesthesiology and Reanimation Clinic, Kızılay Street No. 4, Samanpazarı Altındağ, Ankara, Turkey
3Gülhane Military Medicine Faculty, Anesthesiology and Reanimation Department, Ankara, Turkey

Received 17 April 2013; Revised 17 September 2013; Accepted 8 October 2013; Published 20 January 2014

Academic Editor: Gail B. Mahady

Copyright © 2014 M. Selçuk Yavuz et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Introduction. Postoperative nausea and vomiting (PONV) after laparoscopic cholecystectomy operations still continue to be a serious problem. Intravenous fluid administration has been shown to reduce PONV. Some patients have higher risk for PONV described by APFEL score. In this study, our aim was to determine the effects of preoperative intravenous hydration on postoperative nausea and vomiting in high Apfel scored patients undergoing laparoscopic cholecystectomy surgery. Patients and Methods. This study is performed with 50 female patients who had APFEL score 3-4 after ethics committee approval and informed consent was taken from patients. The patients were divided into 2 groups: group 1 (P1): propofol + preoperative hydration and group 2 (P2): propofol + no preoperative hydration. Results. When the total nausea VAS scores of groups P1 and P2 to which hydration was given or not given were compared, a statistically significant difference was detected at 8th and 12th hours ( and ). It was observed that in group P1, which was given hydration, the nausea VAS score was lower. When the total number of patients who had nausea and vomiting in P1 and P2, more patients suffered nausea in P2 group. Discussion. Preoperative hydration may be effective in high Apfel scored patients to prevent postoperative nausea.