High Level of Tregs Is a Positive Prognostic Marker in Patients with HPV-Positive Oral and Oropharyngeal Squamous Cell Carcinomas
Table 2
Comparison of the mean values of immunological characteristics between patients with tumors positive or negative for HPV (for details see materials and methods).
Immunological characteristics
HPV +
HPV −
value
95% CI
value adja
95% CI adja
Mean
Mean
CD8+ (%)
26.6
26.8
0.896
−3.8; 4.3
0.846
0.9; 1.1
CD4+ (%)
44.3
48.0
0.085
−0.5; 7.9
0.199
0.9; 1.0
CD19+ (%)
11.3
4.7
0.332
−4.4; 1.5
0.305
1.0; 1.2
CD3−CD56+16+ (%)
13.6
6.4
0.005
−7.2; −1.3
0.052
1.0; 1.3
CD4+/CD8+
1.8
2.1
0.355
0.1; 7.8
0.451
0.4; 1.5
Tregs (%)
15.9
15.8
0.998
−4.6; 4.6
0.924
0.9; 1.1
CD8+CD4+sum
70.9
74.8
0.355
0.1; 7.8
0.116
0.9; 1.0
CD8+/Tregs
2.4
3.5
0.258
−0.8; 3.0
0.455
0.7; 1.1
adjusted for age. 95% CI: confidence interval; : probability.