Noninvasive and Quantitative Assessment of In Vivo Fetomaternal Interface Angiogenesis Using RGD-Based Fluorescence
Figure 2
Imaging sequence performed for the gravid mice angiogenesis assay. Panel (a): intravenous injection of Angiolone-Alexa-Fluor 700 on day 6.5 or 11.5 dpc. Panel (b): 2D in vivo fluorescence. Vascularization was imaged using the fDOT2D system. Panel (c): 2D fluorescence images in the uterine horns. Panel (d): 2D fluorescence images in isolated placentas. Panel (e): a hybrid image of placentas in an anatomical context. The scale is provided in arbitrary unit because the fluorescence produces relative values unless a standard calibration has been performed.
