Research Article

Evaluation and Comparison of Multiple Aligners for Next-Generation Sequencing Data Analysis

Figure 3

Graphical representation shows a comparison of various memory usage plots against multiple aligners. With real-life short-read datasets sampled from various organisms by Illumina sequencing platform, (a) shows the memory usage requirements of multiple aligners in single-thread mode, (b) shows the memory usage requirements of multiple aligners in three-thread mode, and (c) shows correlations among read count, genome size, and memory usage. Two short-read datasets (e.g., 5 million reads and 18 million reads) from H. sapiens were chosen to perform comparative analysis. In addition, (d) shows the memory usage requirements of multiple aligners with real-life long-read datasets produced by Roche 454 platform.
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(a)
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(b)
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(c)
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(d)