Improved Variant Calling Accuracy by Merging Replicates in Whole-Exome Sequencing Studies
Figure 3
Comparison of SNPs identified across the on-target and off-target regions in three groups (M, L, and H). (a) Each red circle denotes the number of SNPs detected in the three groups within two regions (ON and OFF). (b) Overlapping rate of the SNPs detected in the H (-axis) and L (-axis) groups with the M group. Each dot denotes the overlapping rate of SNPs across the ON (red) and OFF (black) regions in each corresponding exome. ON and OFF represent the on-target and off-target regions, respectively; M, L, and H represent the merged, low depth, and high depth groups, respectively.
