Cell Communication in a Coculture System Consisting of Outgrowth Endothelial Cells and Primary Osteoblasts
Figure 3
Protein concentration of growth factors contributing to angio- and osteogenesis. Supernatants of direct cocultures, monocultures (left), and four-week cultivated indirect cocultures (right) were collected and VEGF-A (aa′), Ang1 (bb′), PDGF-B (cc′), BMP-4 (dd′), and IGF-1 (ee′) protein concentrations measured to give the distribution throughout the different culture types. The indirect cocultures confirmed the sources of the examined growth factors known from the literature. (*) .
