Research Article
Association Analysis between g.18873C>T and g.27522G>A Genetic Polymorphisms of OPG and Bone Mineral Density in Chinese Postmenopausal Women
Table 2
Genotypic and allelic frequencies of OPG genetic polymorphisms in the studied subjects.
| | Groups | g.18873C>T | g.27522G>A | | Genotypic frequencies (%) | Allelic frequencies (%) | Genotypic frequencies (%) | Allelic frequencies (%) | | CC | CT | TT | C | T | | | GG | GA | AA | G | A | | |
| | Case group ( = 463) | 201 (43.41) | 191 (41.25) | 71 (15.33) | 593 (64.04) | 333 (35.96) | 5.0402 | 0.0805 | 216 (46.65) | 185 (39.96) | 62 (13.39) | 617 (66.63) | 309 (33.37) | 4.7659 | 0.0923 | | Control group ( = 465) | 237 (50.97) | 185 (39.78) | 43 (9.25) | 659 (70.86) | 271 (29.14) | 0.6234 | 0.7322 | 226 (48.60) | 208 (44.73) | 31 (6.67) | 660 (70.97) | 270 (29.03) | 3.4010 | 0.1826 |
| | Total ( = 928) | 438 (47.20) | 376 (40.52) | 114 (12.28) | 1252 (67.46) | 604 (32.54) | 5.5256 | 0.0631 | 442 (47.63) | 393 (42.35) | 93 (10.02) | 1277 (68.80) | 579 (31.20) | 0.1689 | 0.9190 |
| | | ,
= 0.00700 | = 9.8349, = 0.0017 | | | = 11.9014,
= 0.0026 | = 4.0663,
= 0.0437 | | |
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