Association Analysis between g.18873C>T and g.27522G>A Genetic Polymorphisms of OPG and Bone Mineral Density in Chinese Postmenopausal Women
Table 3
Characteristics of OPG genetic polymorphisms in the total group of subjects.
SNPs
g.18873C>T
g.27522G>A
Genotype
CC
CT
TT
GG
GA
AA
Number (%)
438 (47.20)
376 (40.52)
114 (12.28)
—
442 (47.63)
393 (42.35)
93 (10.02)
—
Age (years)
62.5 ± 7.8
62.7 ± 7.9
62.9 ± 6.6
0.345
61.9 ± 7.7
62.8 ± 7.9
62.9 ± 8.3
0.432
Weight (kg)
61.8 ± 6.6
62.5 ± 7.2
62.8 ± 7.2
0.236
61.5 ± 8.2
62.2 ± 6.2
62.7 ± 7.2
0.158
Height (cm)
162 ± 7.7
163 ± 6.8
165 ± 6.1
0.333
158 ± 8.5
162 ± 7.3
165 ± 6.1
0.562
BMI
23.1 ± 3.76
23.3 ± 3.55
23.5 ± 3.27
0.347
23.3 ± 3.56
23.5 ± 3.11
23.7 ± 3.26
0.256
Spine BMD (g/cm2)
0.931 ± 0.111
0.842 ± 0.224
0.830 ± 0.189
0.018
0.942 ± 0.102
0.856 ± 0.114
0.843 ± 0.119
0.028
Neck hip BMD (g/cm2)
0.752 ± 0.106
0.689 ± 0.126
0.679 ± 0.134
0.038
0.744 ± 0.176
0.682 ± 0.117
0.677 ± 0.198
0.037
Total hip BMD (g/cm2)
0.871 ± 0.123
0.814 ± 0.155
0.80 ± 0.187
0.042
0.869 ± 0.105
0.817 ± 0.158
0.810 ± 0.169
0.047
Note: SNPs, single-nucleotide polymorphisms; BMI, body mass index; BMD, bone mineral density; data are shown as mean ± SD (BMD values adjusted by age, weight, and height).
