Attenuation of Collagen-Induced Arthritis in Rat by Nicotinic Alpha7 Receptor Partial Agonist GTS-21
Figure 5
Osteoclast observation (the blank arrows). Tissue sections were stained with TRAP and restained with hematoxylin (original magnification ×100). (a) Control group treated with PBS; (b) group treated with GTS-21 concentration of 1 mg/kg; (c) group treated with GTS-21 concentration of 2.5 mg/kg; (d) statistical data of osteoclasts score in the knee joints of three different groups. ** versus PBS control group. Data represent mean + standard errors of the mean and are representative of eight rats per group.